Scope of application:
Alternating diagnoses mimicking vasculitis should be excluded prior to application of the criteria. When a diagnosis of medium-vessel or large-vessel vasculitis has been made, the classification criteria should be applied to classify the patient as Takayasu Arteritis.
Absolute Requirements:
Age upto 60 years at time of diagnosis
Evidence of vasculitis on imaging: evidence of vasculitis in the aorta or branch arteries must be confirmed by vascula imaging – CT /Catheter-based / MR angiography, Ultrasound, PET
Additional Clinical Criteria:
Female Sex: 1
Systolic blood pressure difference in arms 20 mmHg or more : 1
Angina or ischemic chest pain: 2
Arm or Leg Claudication: 2
Vascular Bruit: 2 (on auscultation of a large artery – aorta, carotid, subclavian, axillary, brachial, renal or ileofemoral arteries)
Reduced pulse in upper extremity: 2 (reduction or absence of pulse by physical examination of axillary, brachial or radial arteries)
Carotid artery abnormality: 2 (reduction or absence of pulse or tenderness)
Additional Imaging Criteria
Number of affected arterial territories (with luminal damage e.g, stenosis, occlusion or aneurysm detected by angiography or ultrasonography in any of the nine territories: thoracic aorta, abdominal aorta, mesenteric, left or right carotid, left or right subclavian, left or right renal arteries): One has to be selected:
One arterial territory: 1
Two arterial territory: 2
Three arterial territory: 3
Symmetric involvement of paired arteries : 1 (bilateral luminal damage in any of carotid, subclavian or renal arteries.
Abdominal aorta involvement with renal or mesenteric involvement: 3 (stenosis, occlusion or aneurysm detected by angiography or ultrasonography of.abdmonial aorta and either the renal or or mesenteric arteries)
The scores of 10 items are summed. A score of 5 or more is needed for classification of Takayasu Arteritis.
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